Anti-CBX5 Monoclonal Antibody

品牌：solarbio | 货号：K000013M

宿主 Mouse 英文名称 Anti-CBX5 Monoclonal Antibody 别名 HEL25;HP1;HP1A;HP1 alpha 应用 WB ICC IHC 稀释比例 WB 1:1000. ICC 1:300. 交叉反应 Human Mouse 蛋白分子量 22kDa Gene ID 23468 保存 Store at -20°C. Avoid freeze / thaw cycles. 储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. 纯化方法 Affinity purification 亚型 IgG2b 免疫原 Purified recombinant human HP1 alpha protein  fragments expressed in E.coli. 性状 液体 Public  Immunogen  Range Purified recombinant human HP1 alpha protein  fragments expressed in E.coli. Subcellular  Locations Chromosome Nucleus centromere Swiss Prot P45973 克隆号 3G2-H10-A6 克隆类型 Monoclonal Antibody 背景资料 This gene encodes a highly conserved nonhistone  protein, which is a member of the heterochromatin  protein family. The protein is enriched in the  heterochromatin and associated with centromeres. The  protein has a single N-terminal chromodomain which  can bind to histone proteins via methylated lysine  residues, and a C-terminal chromo shadow-domain  (CSD) which is responsible for the homodimerization  and interaction with a number of chromatin-associated  nonhistone proteins. The encoded product is involved  in the formation of functional kinetochore through  interaction with essential kinetochore proteins. The  gene has a pseudogene located on chromosome 3.  Multiple alternatively spliced variants, encoding the  same protein, have been identified.