Anti-SRPX Polyclonal Antibody
产品名称： Anti-SRPX Polyclonal Antibody
英文名称： Anti-SRPX Polyclonal Antibody
产品编号： K002453P
产品价格： null
产品产地： 北京
品牌商标： solarbio
更新时间： 2025-02-08T13:37:52
使用范围： WB IHC
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
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- 所在区域 : 北京
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Anti-SRPX Polyclonal Antibody
品牌：solarbio | 货号：K002453P
| 英文名称 | Anti-SRPX Polyclonal Antibody |
|---|---|
| 别名 | DRS;ETX1;HEL-S-83p;SRPX1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 52kDa |
| Gene ID | 8406 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SRPX |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SRPX |
| Subcellular Locations | Cell surface |
| Swiss Prot | P78539 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | X-linked retinitis pigmentosa (XLRP) is a retinal degeneration disorder. The most common form of XLRP has been localized to the gene locus RP3 by linkage and deletion analysis. RP3 maps to chromosome Xp21.1 between CYBB and OTC. The sushi-repeat-containing protein, x chromosome (SRPX) gene, also designated ETX1, resides within this region and is deleted in XLRP patients. There are at least two splice variants of SRPX, one of which contains a thirty amino acid signal peptide. Both variants contain three complement control protein domains, a hydrophobic region for membrane anchorage, and a cytoplasmic carboxy terminus. SRPX is expressed in retina and heart. SRPX is highly homologous to the drs (downregulated by v-src) human homolog, which suggests a role for SRPX as a tumor suppressor. |